| Pos | Équipe | Joués | Victoires | Nuls | Défaites | +/- | Diff | PTS | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Nashville SC |
33 | 22 | 8 | 3 | 69-25 | 44 | 74 | WDWDW |
| 2 |  Inter Miami |
33 | 16 | 11 | 6 | 77-56 | 21 | 59 | WWLDW |
| 3 |  New England Revolution |
33 | 18 | 4 | 11 | 55-46 | 9 | 58 | WWWWL |
| 4 |  Chicago Fire |
33 | 16 | 7 | 10 | 61-50 | 11 | 55 | LLWDW |
| 5 |  Charlotte |
33 | 15 | 8 | 10 | 63-48 | 15 | 53 | LDLWW |
| 6 |  Philadelphia Union |
33 | 13 | 8 | 12 | 62-51 | 11 | 47 | WDLDL |
| 7 |  FC Cincinnati |
33 | 12 | 10 | 11 | 67-73 | -6 | 46 | LWWDW |
| 8 |  Columbus Crew |
33 | 13 | 5 | 15 | 55-49 | 6 | 44 | WWWWW |
| 9 |  Orlando City SC |
33 | 12 | 7 | 14 | 62-78 | -16 | 43 | DWDDL |
| 10 |  New York Red Bulls |
33 | 11 | 6 | 16 | 45-62 | -17 | 39 | LLWLL |
| 11 |  New York City FC |
33 | 9 | 12 | 12 | 48-45 | 3 | 39 | LDDWD |
| 12 |  Toronto FC |
33 | 9 | 12 | 12 | 51-63 | -12 | 39 | DWLWL |
| 13 |  Atlanta United FC |
33 | 9 | 6 | 18 | 43-57 | -14 | 33 | WLLLW |
| 14 |  DC United |
33 | 7 | 12 | 14 | 39-60 | -21 | 33 | LLLLL |
| 15 |  CF Montreal |
33 | 6 | 8 | 19 | 37-67 | -30 | 26 | LDLLD |
| Pos | Équipe | Joués | Victoires | Nuls | Défaites | +/- | Diff | PTS | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Vancouver Whitecaps |
33 | 18 | 7 | 8 | 72-34 | 38 | 61 | DWLWW |
| 2 |  FC Dallas |
33 | 15 | 10 | 8 | 59-50 | 9 | 55 | WDWLD |
| 3 |  San Jose Earthquakes |
33 | 14 | 10 | 9 | 56-48 | 8 | 52 | DDLDW |
| 4 |  St. Louis City |
33 | 14 | 9 | 10 | 58-48 | 10 | 51 | DLLLL |
| 5 |  Houston Dynamo |
33 | 14 | 9 | 10 | 43-42 | 1 | 51 | DDDWL |
| 6 |  Los Angeles FC |
33 | 12 | 11 | 10 | 51-38 | 13 | 47 | DWDDL |
| 7 |  Los Angeles Galaxy |
33 | 11 | 11 | 11 | 49-55 | -6 | 44 | LWDDW |
| 8 |  Portland Timbers |
33 | 12 | 7 | 14 | 60-61 | -1 | 43 | LDWWW |
| 9 |  Colorado Rapids |
33 | 12 | 7 | 14 | 46-47 | -1 | 43 | DDWDL |
| 10 |  Seattle Sounders |
33 | 11 | 10 | 12 | 42-45 | -3 | 43 | LDDLL |
| 11 |  Real Salt Lake |
33 | 12 | 6 | 15 | 51-51 | 0 | 42 | DWWWL |
| 12 |  Minnesota United FC |
33 | 10 | 11 | 12 | 53-57 | -4 | 41 | DWDWW |
| 13 |  San Diego |
33 | 9 | 11 | 13 | 57-62 | -5 | 38 | DDDLW |
| 14 |  Austin |
33 | 8 | 10 | 15 | 42-63 | -21 | 34 | LLWLL |
| 15 |  Sporting Kansas City |
33 | 6 | 5 | 22 | 39-81 | -42 | 23 | LLLLD |
