| Posizione | Squadra | Giocate | Vittorie | Pareggi | Sconfitte | +/- | Differenza reti | Punti | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Inter Miami |
34 | 22 | 8 | 4 | 79-49 | 30 | 74 | DDWWW |
| 2 |  Columbus Crew |
34 | 19 | 9 | 6 | 72-40 | 32 | 66 | DLWWW |
| 3 |  FC Cincinnati |
34 | 18 | 5 | 11 | 58-48 | 10 | 59 | DLLLW |
| 4 |  Orlando City SC |
34 | 15 | 7 | 12 | 59-50 | 9 | 52 | LWWWL |
| 5 |  Charlotte |
34 | 14 | 9 | 11 | 46-37 | 9 | 51 | WDWWW |
| 6 |  New York City FC |
34 | 14 | 8 | 12 | 54-49 | 5 | 50 | DWWWL |
| 7 |  New York Red Bulls |
34 | 11 | 14 | 9 | 55-50 | 5 | 47 | DLWLL |
| 8 |  Montreal Impact |
34 | 11 | 10 | 13 | 48-64 | -16 | 43 | WWWLW |
| 9 |  Atlanta United FC |
34 | 10 | 10 | 14 | 46-49 | -3 | 40 | DDLWW |
| 10 |  DC United |
34 | 10 | 10 | 14 | 52-70 | -18 | 40 | LDWWL |
| 11 |  Toronto FC |
34 | 11 | 4 | 19 | 40-61 | -21 | 37 | LLDLL |
| 12 |  Philadelphia Union |
34 | 9 | 10 | 15 | 62-55 | 7 | 37 | WDLLL |
| 13 |  Nashville SC |
34 | 9 | 9 | 16 | 38-54 | -16 | 36 | DLLLW |
| 14 |  New England Revolution |
34 | 9 | 4 | 21 | 37-74 | -37 | 31 | WLLLL |
| 15 |  Chicago Fire |
34 | 7 | 9 | 18 | 40-62 | -22 | 30 | LLDLL |
| Posizione | Squadra | Giocate | Vittorie | Pareggi | Sconfitte | +/- | Differenza reti | Punti | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Los Angeles FC |
34 | 19 | 7 | 8 | 63-43 | 20 | 64 | WWWWW |
| 2 |  Los Angeles Galaxy |
34 | 19 | 7 | 8 | 69-50 | 19 | 64 | LWWWL |
| 3 |  Real Salt Lake |
34 | 16 | 11 | 7 | 65-48 | 17 | 59 | DDDWW |
| 4 |  Seattle Sounders |
34 | 16 | 9 | 9 | 51-35 | 16 | 57 | DWWWD |
| 5 |  Houston Dynamo |
34 | 15 | 9 | 10 | 47-39 | 8 | 54 | WLWLW |
| 6 |  Minnesota United FC |
34 | 15 | 7 | 12 | 58-49 | 9 | 52 | WWDWW |
| 7 |  Colorado Rapids |
34 | 15 | 5 | 14 | 61-60 | 1 | 50 | WLLLL |
| 8 |  Vancouver Whitecaps |
34 | 13 | 8 | 13 | 52-49 | 3 | 47 | DLLLL |
| 9 |  Portland Timbers |
34 | 12 | 11 | 11 | 65-56 | 9 | 47 | DDLDD |
| 10 |  Austin |
34 | 11 | 9 | 14 | 39-48 | -9 | 42 | LDWLW |
| 11 |  FC Dallas |
34 | 11 | 8 | 15 | 54-56 | -2 | 41 | WLLDW |
| 12 |  St. Louis City |
34 | 8 | 13 | 13 | 50-63 | -13 | 37 | WWLWL |
| 13 |  Sporting Kansas City |
34 | 8 | 7 | 19 | 51-66 | -15 | 31 | WLLLL |
| 14 |  San Jose Earthquakes |
34 | 6 | 3 | 25 | 41-78 | -37 | 21 | LLWLL |
